IL4R Antibody (C-term) [APR04621G]
Product Specifications
Background
Tissue Location: Isoform 1 and isoform 2 are highly expressed in activated T-cells
Synonyms
Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, CD124, Soluble interleukin-4 receptor subunit alpha, Soluble IL-4 receptor subunit alpha, Soluble IL-4R-alpha, sIL4Ralpha/prot, IL-4-binding protein, IL4-BP, IL4R, IL4RA
Gene Name
IL4R
Gene ID
3566
UniProt
P24394
Chromosomal Location
Cell membrane; Single-pass type I membrane protein
Applications
WB, FC
Dilution
FC--1:25 WB--1:1000
Function
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
Molecular Weight
89658
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL4R Antibody (C-term) [APR04621G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3566
Uniprot URL
https://www.uniprot.org/uniprot/P24394
Available Sizes
Curated Selection
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