UBE3C Antibody (Center) [APR04583G]
Product Specifications
Background
Tissue Location: Highly expressed in skeletal muscle. Detected at much lower levels in kidney and pancreas.
Synonyms
Ubiquitin-protein ligase E3C, 632-, HectH2, UBE3C, KIAA0010, KIAA10
Gene Name
UBE3C
Gene ID
9690
UniProt
Q15386
Chromosomal Location
Nucleus.
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys- 48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
Molecular Weight
123923
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UBE3C Antibody (Center) [APR04583G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=9690
Uniprot URL
https://www.uniprot.org/uniprot/Q15386
Available Sizes
Curated Selection
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