Mouse Camkk2 Antibody (N-term) [APR04046G]
Product Specifications
Background
Tissue Location: Expressed in all tissues tested. A differential expression pattern compared to CAMKK1 is observed in the brain
Synonyms
Calcium/calmodulin-dependent protein kinase kinase 2, CaM-KK 2, CaM-kinase kinase 2, CaMKK 2, Calcium/calmodulin-dependent protein kinase kinase beta, CaM-KK beta, CaM-kinase kinase beta, CaMKK beta, Camkk2, Kiaa0787
Gene Name
Camkk2
Gene ID
207565
UniProt
Q8C078
Chromosomal Location
Nucleus {ECO:0000250|UniProtKB:Q96RR4}. Cytoplasm {ECO:0000250|UniProtKB:Q96RR4}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q96RR4}. Note=Predominantly nuclear in unstimulated cells, relocalizes into cytoplasm and neurites after forskolin induction. {ECO:0000250|UniProtKB:Q96RR4}
Applications
WB
Dilution
WB--1:2000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK4 and CAMK1D (By similarity) . Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca (2+) signals (By similarity) . May play a role in neurite growth. Isoform 2 may promote neurite elongation, while isoform 1 may promoter neurite branching (By similarity) . May be involved in hippocampal activation of CREB1.
Molecular Weight
64618
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Mouse Camkk2 Antibody (N-term) [APR04046G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=207565
Uniprot URL
https://www.uniprot.org/uniprot/Q8C078
Available Sizes
Curated Selection
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