URG4 Antibody (Center) [APR06220G]

Product Specifications

Background

Tissue Location: Strongly expressed in hepatitis B virus-infected liver and in HCC cells. Also highly expressed in well-differentiated gastric cancer tissues and various gastric cancer cell lines

Synonyms

Up-regulator of cell proliferation, HBV X protein up-regulated gene 4 protein, HBxAg up-regulated gene 4 protein, URGCP, KIAA1507 {ECO:0000312|EMBL:BAA960311}, URG4

Gene Name

URGCP

Gene ID

55665

UniProt

Q8TCY9

Chromosomal Location

Cytoplasm. Nucleus. Note=In epithelial cells localized predominantly in the cytoplasm and occasionally in nuclei

Applications

IHC-P, WB

Dilution

WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer.

Molecular Weight

104987

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality URG4 Antibody (Center) [APR06220G].