ZRANB1 Antibody (C-term) [APR06203G]
Product Specifications
Background
Tissue Location: Widely expressed..
Synonyms
Ubiquitin thioesterase ZRANB1, TRAF-binding domain-containing protein, hTrabid, Zinc finger Ran-binding domain-containing protein 1, ZRANB1, TRABID
Gene Name
ZRANB1
Gene ID
54764
UniProt
Q9UGI0
Chromosomal Location
Cytoplasm. Nucleus. Note=Enriched in punctate localization in the cytoplasm
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Specifically hydrolyzes 'Lys-29'-linked and 'Lys-33'-linked diubiquitin. Also cleaves 'Lys-63'-linked chains, but with 40-fold less efficiency compared to 'Lys-29'-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling.
Molecular Weight
80967
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ZRANB1 Antibody (C-term) [APR06203G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=54764
Uniprot URL
https://www.uniprot.org/uniprot/Q9UGI0
Available Sizes
Curated Selection
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