AGR3 Antibody (C-term) [APR06168G]

Product Specifications

Background

Tissue Location: Expressed in the lung, in the ciliated cells of the airway epithelium (PubMed:25751668) . Expression increased with differentiation of airway epithelial cells (PubMed:25751668) . Not detected in the mucous cells (PubMed:25751668) . Expressed in ciliated cells in the oviduct (PubMed:26170690) . Also detected in stomach, colon, prostate and liver (PubMed:25751668) . Expressed in breast, ovary, prostate and liver cancer (PubMed:26170690) . Expression is associated with the level of differentiation of breast cancer (at protein level) (PubMed:26170690) .

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AGR3 Antibody (C-term) [APR06168G].

Synonyms

Anterior gradient protein 3 homolog, AG-3, AG3, hAG-3, Breast cancer membrane protein 11, AGR3, BCMP11

Gene Name

AGR3

Gene ID

155465

UniProt

Q8TD06

Chromosomal Location

Endoplasmic reticulum. Note=Found in the cytoplasm, which could include the endoplasmic reticulum

Applications

WB, IHC-P, FC

Dilution

WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells.