AGR3 Antibody (C-term) [APR06168G]
Product Specifications
Background
Tissue Location: Expressed in the lung, in the ciliated cells of the airway epithelium (PubMed:25751668) . Expression increased with differentiation of airway epithelial cells (PubMed:25751668) . Not detected in the mucous cells (PubMed:25751668) . Expressed in ciliated cells in the oviduct (PubMed:26170690) . Also detected in stomach, colon, prostate and liver (PubMed:25751668) . Expressed in breast, ovary, prostate and liver cancer (PubMed:26170690) . Expression is associated with the level of differentiation of breast cancer (at protein level) (PubMed:26170690) .
Synonyms
Anterior gradient protein 3 homolog, AG-3, AG3, hAG-3, Breast cancer membrane protein 11, AGR3, BCMP11
Gene Name
AGR3
Gene ID
155465
UniProt
Q8TD06
Chromosomal Location
Endoplasmic reticulum. Note=Found in the cytoplasm, which could include the endoplasmic reticulum
Applications
WB, IHC-P, FC
Dilution
WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells.
Molecular Weight
19171
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AGR3 Antibody (C-term) [APR06168G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=155465
Uniprot URL
https://www.uniprot.org/uniprot/Q8TD06
Available Sizes
Curated Selection
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