RAC1 Antibody (S71) [APR05940G]
Product Specifications
Background
Tissue Location: Isoform B is predominantly identified in skin and epithelial tissues from the intestinal tract. Its expression is elevated in colorectal tumors at various stages of neoplastic progression, as compared to their respective adjacent tissues
Synonyms
Ras-related C3 botulinum toxin substrate 1, Cell migration-inducing gene 5 protein, Ras-like protein TC25, p21-Rac1, RAC1, TC25
Gene Name
HGNC:9801
Gene ID
5879
UniProt
P63000
Chromosomal Location
Cell membrane; Lipid-anchor; Cytoplasmic side. Melanosome. Cytoplasm Cell projection, lamellipodium {ECO:0000250|UniProtKB:P63001}. Cell projection, dendrite {ECO:0000250|UniProtKB:P63001}. Cell junction, synapse {ECO:0000250|UniProtKB:Q6RUV5}. Note=Inner surface of plasma membrane possibly with attachment requiring prenylation of the C- terminal cysteine (PubMed:1903399) . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065) . Found in the ruffled border (a late endosomal-like compartment in the plasma membrane) of bone-resorbing osteoclasts. Localizes to the lamellipodium in a SH3RF1-dependent manner (By similarity) . In macrophages, cytoplasmic location increases upon CSF1 stimulation (By similarity) {ECO:0000250|UniProtKB:P63001, ECO:0000250|UniProtKB:Q6RUV5, ECO:0000269|PubMed:17081065, ECO:0000269|PubMed:1903399}
Applications
WB
Dilution
WB--1:2000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
1643658288863459121475164365812695502
Molecular Weight
21450
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RAC1 Antibody (S71) [APR05940G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5879
Uniprot URL
https://www.uniprot.org/uniprot/P63000
Available Sizes
Curated Selection
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