CAMK1D Antibody (N-term) [APR05855G]
Product Specifications
Background
Tissue Location: Widely expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes.
Synonyms
Calcium/calmodulin-dependent protein kinase type 1D, CaM kinase I delta, CaM kinase ID, CaM-KI delta, CaMKI delta, CaMKID, CaMKI-like protein kinase, CKLiK, CAMK1D, CAMKID
Gene Name
CAMK1D
Gene ID
57118
UniProt
Q8IU85
Chromosomal Location
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Nuclear localization increases upon activation by KCl treatment in hippocampal neurons
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium- mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta.
Molecular Weight
42914
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CAMK1D Antibody (N-term) [APR05855G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=57118
Uniprot URL
https://www.uniprot.org/uniprot/Q8IU85
Available Sizes
Curated Selection
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