GAB2 Antibody (N-term) [APR05817G]
Product Specifications
Synonyms
GRB2-associated-binding protein 2, GRB2-associated binder 2, Growth factor receptor bound protein 2-associated protein 2, pp100, GAB2, KIAA0571
Gene Name
GAB2
Gene ID
9846
UniProt
Q9UQC2
Chromosomal Location
Cytoplasm. Cell membrane
Applications
FC, WB
Dilution
WB--1:1000 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Molecular Weight
74458
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GAB2 Antibody (N-term) [APR05817G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=9846
Uniprot URL
https://www.uniprot.org/uniprot/Q9UQC2
Available Sizes
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