TCPR1 Antibody (N-term) [APR05812G]
Product Specifications
Synonyms
Tectonin beta-propeller repeat-containing protein 1, TECPR1, KIAA1358
Gene Name
TECPR1
Gene ID
25851
UniProt
Q7Z6L1
Chromosomal Location
Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome membranes, and binds PtdIns (3) P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes
Applications
IHC-P, WB, FC
Dilution
IHC-P--1:100~500 WB--1:1000 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns (3) P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.
Molecular Weight
129696
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TCPR1 Antibody (N-term) [APR05812G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=25851
Uniprot URL
https://www.uniprot.org/uniprot/Q7Z6L1
Available Sizes
Curated Selection
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