MTM1 Antibody (C-term) [APR05808G]
Product Specifications
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MTM1 Antibody (C-term) [APR05808G].
Synonyms
Myotubularin, Phosphatidylinositol-3,5-bisphosphate 3-phosphatase, Phosphatidylinositol-3-phosphate phosphatase, MTM1, CG2
Gene Name
HGNC:7448
Gene ID
4534
UniProt
Q13496
Chromosomal Location
Cytoplasm. Cell membrane; Peripheral membrane protein. Cell projection, filopodium. Cell projection, ruffle. Late endosome. Cytoplasm, myofibril, sarcomere {ECO:0000250|UniProtKB:Q9Z2C5}. Note=Localizes as a dense cytoplasmic network (PubMed:11001925) . Also localizes to the plasma membrane, including plasma membrane extensions such as filopodia and ruffles (PubMed:12118066) . Predominantly located in the cytoplasm following interaction with MTMR12 (PubMed:12847286) . Recruited to the late endosome following EGF stimulation (PubMed:14722070) . In skeletal muscles, co-localizes with MTMR12 in the sarcomere (By similarity) {ECO:0000250|UniProtKB:Q9Z2C5, ECO:0000269|PubMed:11001925, ECO:0000269|PubMed:12118066, ECO:0000269|PubMed:12847286, ECO:0000269|PubMed:14722070}
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Function
1100192510900271126461341472207095374141472207021135508211355082113550823818870
Molecular Weight
69932
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4534
Uniprot URL
https://www.uniprot.org/uniprot/Q13496
Available Sizes
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