HLA-DRA Antibody (C-term) [APR05805G]
Product Specifications
Background
Tissue Location: Expressed in professional APCs: macrophages, dendritic cells and B cells (at protein level) (PubMed:31495665, PubMed:15322540, PubMed:23783831) . Expressed in thymic epithelial cells (at protein level) (PubMed:23783831) .
Synonyms
HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen DRA, HLA-DRA, HLA-DRA1
Gene Name
HLA-DRA
Gene ID
3122
UniProt
P01903
Chromosomal Location
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Autolysosome membrane; Single-pass type I membrane protein. Note=The MHCII complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation (PubMed:9075930, PubMed:18305173) . Component of immunological synapses at the interface between T cell and APC (PubMed:15322540, PubMed:29884618) .
Applications
WB, FC
Dilution
WB--1:1000 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
2988461817334368814581915322540223270722759132331495665152659319075930241904318145819314956651718226223783831254130138145819
Molecular Weight
28621
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HLA-DRA Antibody (C-term) [APR05805G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3122
Uniprot URL
https://www.uniprot.org/uniprot/P01903
Available Sizes
Curated Selection
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