ST14 Antibody (C-term) [APR05724G]
Product Specifications
Synonyms
Suppressor of tumorigenicity 14 protein, Matriptase, Membrane-type serine protease 1, MT-SP1, Prostamin, Serine protease 14, Serine protease TADG-15, Tumor-associated differentially-expressed gene 15 protein, ST14, PRSS14, SNC19, TADG15
Gene Name
ST14
Gene ID
6768
UniProt
Q9Y5Y6
Chromosomal Location
Membrane; Single-pass type II membrane protein
Applications
WB, IHC-P
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing.
Molecular Weight
94770
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ST14 Antibody (C-term) [APR05724G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6768
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y5Y6
Available Sizes
Curated Selection
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