REG3G Antibody (Center) [APR05660G]

Product Specifications

Background

Tissue Location: Predominantly expressed in pancreas, where it may be restricted to exocrine pancreas. Moderate expression levels in testis and weak in heart, kidney and placenta

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality REG3G Antibody (Center) [APR05660G].

Synonyms

Regenerating islet-derived protein 3-gamma, REG-3-gamma, Pancreatitis-associated protein 1B, PAP-1B, Pancreatitis-associated protein IB, PAP IB, Regenerating islet-derived protein III-gamma, REG III, Reg III-gamma, Regenerating islet-derived protein 3-gamma 165 kDa form, Regenerating islet-derived protein 3-gamma 15 kDa form, REG3G, PAP1B

Gene Name

REG3G

Gene ID

130120

UniProt

Q6UW15

Chromosomal Location

Secreted. Cytoplasm.

Applications

WB, IHC-P, FC

Dilution

WB--1:1000 WB--1:500~1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury.