Phospho-MDM2 (S395) Antibody [APR05209G]
Product Specifications
Background
Tissue Location: Ubiquitous. Isoform Mdm2-A, isoform Mdm2-B, isoform Mdm2-C, isoform Mdm2-D, isoform Mdm2-E, isoform Mdm2-F and isoform Mdm2-G are observed in a range of cancers but absent in normal tissues
Synonyms
E3 ubiquitin-protein ligase Mdm2, 632-, Double minute 2 protein, Hdm2, Oncoprotein Mdm2, p53-binding protein Mdm2, MDM2
Gene Name
MDM2
Gene ID
4193
UniProt
Q00987
Chromosomal Location
Nucleus, nucleoplasm. Cytoplasm. Nucleus, nucleolus. Nucleus. Note=Expressed predominantly in the nucleoplasm. Interaction with ARF (P14) results in the localization of both proteins to the nucleolus. The nucleolar localization signals in both ARF (P14) and MDM2 may be necessary to allow efficient nucleolar localization of both proteins. Colocalizes with RASSF1 isoform A in the nucleus
Applications
DB
Dilution
DB--1:500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
12821780150538801519510015632057163375941729022019098711192190731983767019965871201730982038513320858735221289113087990330879903
Molecular Weight
55233
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-MDM2 (S395) Antibody [APR05209G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4193
Uniprot URL
https://www.uniprot.org/uniprot/Q00987
Available Sizes
Curated Selection
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