Bi-Phospho-YES1 (Y537) /Phospho-SRC (Y530) Antibody [APR05154G]
Product Specifications
Background
Tissue Location: Expressed ubiquitously. Platelets, neurons and osteoclasts express 5-fold to 200-fold higher levels than most other tissues
Synonyms
Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pp60c-src, p60-Src, SRC, SRC1
Gene Name
HGNC:11283
Gene ID
6714
UniProt
P12931
Chromosomal Location
Cell membrane; Lipid-anchor. Mitochondrion inner membrane. Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell junction, focal adhesion. Note=Localizes to focal adhesion sites following integrin engagement (PubMed:22801373) . Localization to focal adhesion sites requires myristoylation and the SH3 domain (PubMed:7525268) . Colocalizes with PDLIM4 at the perinuclear region, but not at focal adhesions (PubMed:19307596)
Applications
DB, IHC-P
Dilution
DB--1:500 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
214116251138973018586953785350787555291458596312615910161861082010083521309750194199661458596322710723205256941930759625731159
Molecular Weight
59835
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Bi-Phospho-YES1 (Y537) /Phospho-SRC (Y530) Antibody [APR05154G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6714
Uniprot URL
https://www.uniprot.org/uniprot/P12931
Available Sizes
Curated Selection
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