Phospho-Rb (S780) Antibody [APR05149G]

Product Specifications

Background

Tissue Location: Expressed in the retina. Expressed in foreskin keratinocytes (at protein level) (PubMed:20940255)

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-Rb (S780) Antibody [APR05149G].

Synonyms

Retinoblastoma-associated protein, p105-Rb, pRb, Rb, pp110, RB1

Gene Name

RB1

Gene ID

5925

UniProt

P06400

Chromosomal Location

Nucleus. Note=During keratinocyte differentiation, acetylation by KAT2B/PCAF is required for nuclear localization.

Applications

WB, DB, IHC-P

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein G affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.