FCGR3B Antibody (N-term) [APR04631G]
Product Specifications
Background
Tissue Location: Expressed specifically by polymorphonuclear leukocytes (neutrophils) . Also expressed by stimulated eosinophils
Synonyms
Low affinity immunoglobulin gamma Fc region receptor III-B, Fc-gamma RIII-beta, Fc-gamma RIII, Fc-gamma RIIIb, FcRIII, FcRIIIb, FcR-10, IgG Fc receptor III-1, CD16b, FCGR3B, CD16B, FCG3, FCGR3, IGFR3
Gene Name
FCGR3B
Gene ID
2215
UniProt
O75015
Chromosomal Location
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Secreted after cleavage
Applications
WB
Dilution
WB--1:1000
Function
Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Molecular Weight
26216
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FCGR3B Antibody (N-term) [APR04631G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2215
Uniprot URL
https://www.uniprot.org/uniprot/O75015
Available Sizes
Curated Selection
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