IL17RE Antibody (N-term) [APR04458G]
Product Specifications
Background
Tissue Location: Predominantly expressed in mucosal tissues with high levels in keratinocytes and colon epithelial cells. Very low expression in dermal fibroblasts. Expressed in various tumor cell lines.
Synonyms
Interleukin-17 receptor E, IL-17 receptor E, IL-17RE, IL17RE
Gene Name
IL17RE
Gene ID
132014
UniProt
Q8NFR9
Chromosomal Location
[Isoform 1]: Cell membrane; Single- pass type I membrane protein [Isoform 3]: Secreted. [Isoform 5]: Secreted.
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors.
Molecular Weight
74810
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL17RE Antibody (N-term) [APR04458G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=132014
Uniprot URL
https://www.uniprot.org/uniprot/Q8NFR9
Available Sizes
Curated Selection
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