What is the catalog number for CTNNB1 Antibody (C-term) [APR04440G]?

The catalog number for CTNNB1 Antibody (C-term) [APR04440G] is APR04440G.

What sizes are available for CTNNB1 Antibody (C-term) [APR04440G]?

CTNNB1 Antibody (C-term) [APR04440G] is available in the following size(s): 50 µL, 100 µL, 200 µL, 400 µL.

How many pack sizes does CTNNB1 Antibody (C-term) [APR04440G] come in?

CTNNB1 Antibody (C-term) [APR04440G] is available in 4 different pack sizes.

Is CTNNB1 Antibody (C-term) [APR04440G] in stock?

CTNNB1 Antibody (C-term) [APR04440G] is currently made to order / not held in immediate stock. Contact us for lead time.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

CTNNB1 Antibody (C-term) [APR04440G]

Product Specifications

Background

Tissue Location: Expressed in several hair follicle cell types: basal and peripheral matrix cells, and cells of the outer and inner root sheaths. Expressed in colon. Present in cortical neurons (at protein level) . Expressed in breast cancer tissues (at protein level) (PubMed:29367600) .

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CTNNB1 Antibody (C-term) [APR04440G].

Synonyms

Catenin beta-1, Beta-catenin, CTNNB1, CTNNB

Gene Name

CTNNB1

Gene ID

1499

UniProt

P35222

Chromosomal Location

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:B6V8E6}. Cell junction, adherens junction {ECO:0000250|UniProtKB:Q02248}. Cell junction {ECO:0000250|UniProtKB:B6V8E6}. Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole Cell junction, synapse {ECO:0000250|UniProtKB:Q02248}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q02248} Note=Colocalized with RAPGEF2 and TJP1 at cell-cell contacts (By similarity) . Cytoplasmic when it is unstabilized (high level of phosphorylation) or bound to CDH1. Translocates to the nucleus when it is stabilized (low level of phosphorylation) . Interaction with GLIS2 and MUC1 promotes nuclear translocation. Interaction with EMD inhibits nuclear localization. The majority of beta-catenin is localized to the cell membrane. In interphase, colocalizes with CROCC between CEP250 puncta at the proximal end of centrioles, and this localization is dependent on CROCC and CEP250. In mitosis, when NEK2 activity increases, it localizes to centrosomes at spindle poles independent of CROCC. Colocalizes with CDK5 in the cell-cell contacts and plasma membrane of undifferentiated and differentiated neuroblastoma cells Interaction with FAM53B promotes translocation to the nucleus (PubMed:25183871) . {ECO:0000250|UniProtKB:B6V8E6, ECO:0000269|PubMed:25183871}

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

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