TIGAR Antibody (N-term) [APR04405G]
Product Specifications
Background
Tissue Location: Expressed in the brain (PubMed:22887998) . Expressed in breast tumors (PubMed:21820150) . Expressed in glioblastomas (PubMed:22887998) .
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TIGAR Antibody (N-term) [APR04405G].
Synonyms
Fructose-2,6-bisphosphatase TIGAR, TP53-induced glycolysis and apoptosis regulator, TIGAR, C12orf5
Gene Name
TIGAR {ECO:0000303|PubMed:16839880}
Gene ID
57103
UniProt
Q9NQ88
Chromosomal Location
Cytoplasm. Nucleus Mitochondrion. Note=Translocated to the mitochondria during hypoxia in a HIF1A-dependent manner (PubMed:23185017) . Colocalizes with HK2 in the mitochondria during hypoxia (PubMed:23185017) . Translocated to the nucleus during hypoxia and/or genome stress-induced DNA damage responses in cancer cells (PubMed:25928429) . Translocation to the mitochondria is enhanced in ischemic cortex after reperfusion and/or during oxygen and glucose deprivation (OGD) /reoxygenation insult in primary neurons (By similarity) . {ECO:0000250|UniProtKB:Q8BZA9, ECO:0000269|PubMed:23185017, ECO:0000269|PubMed:25928429}
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
19015259168398802288799816839880197139382372697322887998238170402318501723726973228879982592842923726973
Molecular Weight
30063
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=57103
Uniprot URL
https://www.uniprot.org/uniprot/Q9NQ88
Available Sizes
Curated Selection
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