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AGTRAP Antibody (C-term) [APR04313G]

Product Specifications

Background

Tissue Location: Ubiquitous but more abundant in kidney, heart, pancreas and thyroid.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AGTRAP Antibody (C-term) [APR04313G].

Synonyms

Type-1 angiotensin II receptor-associated protein, AT1 receptor-associated protein, AGTRAP, ATRAP

Gene Name

AGTRAP

Gene ID

57085

UniProt

Q6RW13

Chromosomal Location

Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles

Applications

WB

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II- stimulated transcriptional activity.

Molecular Weight

17419

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=57085

Uniprot URL

https://www.uniprot.org/uniprot/Q6RW13

Available Sizes

Frequently Asked Questions

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