TEX2 Antibody (Center) [APR04262G]
Product Specifications
Synonyms
Testis-expressed sequence 2 protein, Transmembrane protein 96, TEX2, KIAA1738, TMEM96
Gene Name
TEX2
Gene ID
55852
UniProt
Q8IWB9
Chromosomal Location
Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q06833}; Multi-pass membrane protein. Nucleus membrane {ECO:0000250|UniProtKB:Q06833}; Multi- pass membrane protein. Note=Enriched at the nucleus- vacuole junction (PubMed:22250200) . During endoplasmic reticulum (ER) stress, localizes to ER-Golgi contacts (By similarity) {ECO:0000250|UniProtKB:Q06833, ECO:0000269|PubMed:22250200}
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
During endoplasmic reticulum (ER) stress or when cellular ceramide levels increase, may induce contacts between the ER and medial-Golgi complex to facilitate non-vesicular transport of ceramides from the ER to the Golgi complex where they are converted to complex sphingolipids, preventing toxic ceramide accumulation.
Molecular Weight
125303
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TEX2 Antibody (Center) [APR04262G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=55852
Uniprot URL
https://www.uniprot.org/uniprot/Q8IWB9
Available Sizes
Curated Selection
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