RAB20 Antibody (C-term) [APR04227G]
Product Specifications
Background
Tissue Location: Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level) .
Synonyms
Ras-related protein Rab-20, RAB20
Gene Name
RAB20
Gene ID
55647
UniProt
Q9NX57
Chromosomal Location
Golgi apparatus. Cytoplasmic vesicle, phagosome Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (By similarity) . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211) {ECO:0000250|UniProtKB:P35295, ECO:0000269|PubMed:21255211}
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
Molecular Weight
26277
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RAB20 Antibody (C-term) [APR04227G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=55647
Uniprot URL
https://www.uniprot.org/uniprot/Q9NX57
Available Sizes
Curated Selection
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