CNIH3 Antibody (N-term) [APR04222G]

Product Specifications

Background

Tissue Location: Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study) .

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CNIH3 Antibody (N-term) [APR04222G].

Synonyms

Protein cornichon homolog 3, CNIH-3, Cornichon family AMPA receptor auxiliary protein 3, CNIH3

Gene Name

CNIH3

Gene ID

149111

UniProt

Q8TBE1

Chromosomal Location

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein Note=Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells) .

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs) . Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization.