HECTD3 Antibody (C-term) [APR04212G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HECTD3 Antibody (C-term) [APR04212G].

Synonyms

E3 ubiquitin-protein ligase HECTD3, 632-, HECT domain-containing protein 3, HECTD3

Gene Name

HECTD3

Gene ID

79654

UniProt

Q5T447

Chromosomal Location

Cytoplasm, perinuclear region.

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus facilitating cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8 (By similarity) .