LIN28B Antibody (Center) [APR04032G]
Product Specifications
Background
Tissue Location: Expressed at high levels in the placenta and, at mucher lower, in testis and fetal liver (PubMed:16971064) . Isoform 1 is only detected in placenta and in moderately and poorly differentiated hepatocellular carcinoma cells (at protein level) . Isoform 2 is detected in fetal liver, non-tumor liver tissues, as well as well- differentiated tumor tissues (at protein level) . Tends to be up- regulated in triple-negative (ER-, PR-, HER2-) breast tumors, as well as in liver, ovarian, and thyroid carcinomas (PubMed:22118463)
Synonyms
Protein lin-28 homolog B, Lin-28B, LIN28B, CSDD2
Gene Name
LIN28B
Gene ID
389421
UniProt
Q6ZN17
Chromosomal Location
Nucleus. Nucleus, nucleolus. Cytoplasm Note=Predominantly nucleolar (PubMed:22118463) . In Huh7 cells, predominantly cytoplasmic, with only a subset of cells exhibiting strong nuclear staining; however, the specificity of the polyclonal antibody used in these experiments has not been not documented (PubMed:16971064) .
Applications
IHC-P-Leica, FC, IF, WB
Dilution
WB--1:2000 FC--1:10~50 IF--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
22118463221184631970339622118463
Molecular Weight
27084
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LIN28B Antibody (Center) [APR04032G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=389421
Uniprot URL
https://www.uniprot.org/uniprot/Q6ZN17
Available Sizes
Curated Selection
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