Mouse Frk Antibody (C-term) [APR04026G]
Product Specifications
Background
Tissue Location: Expressed in intestinal tract, fetal and adult islets of Langerhans, kidney, liver and lung
Synonyms
Tyrosine-protein kinase FRK, Beta-cell Src-homology tyrosine kinase, BSK, FYN-related kinase, Intestine tyrosine kinase, Frk, Bsk, Iyk
Gene Name
Frk
Gene ID
14302
UniProt
Q922K9
Chromosomal Location
Cytoplasm. Nucleus. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery.
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity) .
Molecular Weight
58844
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Mouse Frk Antibody (C-term) [APR04026G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=14302
Uniprot URL
https://www.uniprot.org/uniprot/Q922K9
Available Sizes
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