Mouse Frk Antibody (C-term) [APR04026G]

Product Specifications

Background

Tissue Location: Expressed in intestinal tract, fetal and adult islets of Langerhans, kidney, liver and lung

Synonyms

Tyrosine-protein kinase FRK, Beta-cell Src-homology tyrosine kinase, BSK, FYN-related kinase, Intestine tyrosine kinase, Frk, Bsk, Iyk

Gene Name

Frk

Gene ID

14302

UniProt

Q922K9

Chromosomal Location

Cytoplasm. Nucleus. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery.

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity) .

Molecular Weight

58844

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Mouse Frk Antibody (C-term) [APR04026G].