PERP Antibody (C-term) [APR03967G]

Product Specifications

Background

Tissue Location: Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PERP Antibody (C-term) [APR03967G].

Synonyms

P53 apoptosis effector related to PMP-22, Keratinocyte-associated protein 1, KCP-1, P53-induced protein PIGPC1, Transmembrane protein THW, PERP, KCP1, KRTCAP1, PIGPC1, THW

Gene Name

PERP

Gene ID

64065

UniProt

Q96FX8

Chromosomal Location

Cell junction, desmosome {ECO:0000250|UniProtKB:Q9JK95}. Cell membrane {ECO:0000250|UniProtKB:Q9JK95}; Multi-pass membrane protein. Note=Associated with desmosomes {ECO:0000250|UniProtKB:Q9JK95}

Applications

WB, IHC-P

Dilution

WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity) .