Mouse Matk Antibody (C-term) [APR03936G]
Product Specifications
Background
Tissue Location: Most abundant in brain, and to a lesser extent in the spleen, the thymus and the liver. Also found in the T-cell lineage
Synonyms
Megakaryocyte-associated tyrosine-protein kinase, Protein kinase NTK, Tyrosine-protein kinase CTK, Matk, Ctk, Ntk
Gene Name
Matk
Gene ID
17179
UniProt
P41242
Chromosomal Location
Cytoplasm. Membrane. Note=In platelets, 90% of MATK localizes to the membrane fraction, and translocates to the cytoskeleton upon thrombin stimulation.
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC- family members in brain by specifically phosphorylating their C- terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T- cell proliferation.
Molecular Weight
56056
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Mouse Matk Antibody (C-term) [APR03936G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=17179
Uniprot URL
https://www.uniprot.org/uniprot/P41242
Available Sizes
Curated Selection
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