GNAQ Antibody (N-term) [APR03922G]
Product Specifications
Background
Tissue Location: Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level)
Synonyms
Guanine nucleotide-binding protein G (q) subunit alpha, Guanine nucleotide-binding protein alpha-q, GNAQ, GAQ
Gene Name
GNAQ
Gene ID
2776
UniProt
P50148
Chromosomal Location
Cell membrane; Lipid-anchor. Golgi apparatus. Nucleus {ECO:0000250|UniProtKB:P21279} Nucleus membrane {ECO:0000250, ECO:0000250|UniProtKB:P21279} Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes {ECO:0000250|UniProtKB:P21279}
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM- derived neutrophils and dendritic cells (in vitro) (By similarity) . Transduces FFAR4 signaling in response to long-chain fatty acids (LCFAs) .
Molecular Weight
42142
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GNAQ Antibody (N-term) [APR03922G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2776
Uniprot URL
https://www.uniprot.org/uniprot/P50148
Available Sizes
Curated Selection
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