STAM2 Antibody (Center) [APR03900G]
Product Specifications
Background
Tissue Location: Ubiquitously expressed.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality STAM2 Antibody (Center) [APR03900G].
Synonyms
Signal transducing adapter molecule 2, STAM-2, Hrs-binding protein, STAM2, HBP
Gene Name
STAM2
Gene ID
10254
UniProt
O75886
Chromosomal Location
Cytoplasm. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex) . The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity) .
Molecular Weight
58164
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=10254
Uniprot URL
https://www.uniprot.org/uniprot/O75886
Available Sizes
Curated Selection
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