MBL2 Antibody (C-term) [APR03857G]
Product Specifications
Background
Tissue Location: Plasma protein produced mainly in the liver.
Synonyms
Mannose-binding protein C, MBP-C, Collectin-1, MBP1, Mannan-binding protein, Mannose-binding lectin, MBL2, COLEC1, MBL
Gene Name
MBL2
Gene ID
4153
UniProt
P11226
Chromosomal Location
Secreted.
Applications
WB, IF, IHC-P
Dilution
WB--1:1000 IF--1:10~50 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
Molecular Weight
26144
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MBL2 Antibody (C-term) [APR03857G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4153
Uniprot URL
https://www.uniprot.org/uniprot/P11226
Available Sizes
Curated Selection
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