MBL2 Antibody (C-term) [APR03857G]

Product Specifications

Background

Tissue Location: Plasma protein produced mainly in the liver.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MBL2 Antibody (C-term) [APR03857G].

Synonyms

Mannose-binding protein C, MBP-C, Collectin-1, MBP1, Mannan-binding protein, Mannose-binding lectin, MBL2, COLEC1, MBL

Gene Name

MBL2

Gene ID

4153

UniProt

P11226

Chromosomal Location

Secreted.

Applications

WB, IF, IHC-P

Dilution

WB--1:1000 IF--1:10~50 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.