TGFBRAP1 Antibody (C-term) [APR03814G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TGFBRAP1 Antibody (C-term) [APR03814G].

Synonyms

Transforming growth factor-beta receptor-associated protein 1, TGF-beta receptor-associated protein 1, TRAP-1, TRAP1, TGFBRAP1

Gene Name

TGFBRAP1

Gene ID

9392

UniProt

Q8WUH2

Chromosomal Location

Cytoplasm. Early endosome. Note=Colocalizes with TGF-beta receptors in the absence of signaling

Applications

WB, IHC-P

Dilution

WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2.