SC65 Antibody (C-term) [APR03794G]

Product Specifications

Background

Tissue Location: Detected in fibroblasts (at protein level) (PubMed:23959653) . Detected in spleen, prostate, testis, ovary, colon, pancreas, kidney, placenta and heart (PubMed:10952778)

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SC65 Antibody (C-term) [APR03794G].

Synonyms

Synaptonemal complex protein SC65, Leprecan-like protein 4, Nucleolar autoantigen No55, LEPREL4, NOL55, SC65

Gene Name

HGNC:16946

Gene ID

10609

UniProt

Q92791

Chromosomal Location

Endoplasmic reticulum

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils. Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly.