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KLRC1 Antibody (N-term) [APR03712G]

Product Specifications

Background

Tissue Location: Predominantly expressed in NK cells (at protein level) (PubMed:9430220, PubMed:9485206, PubMed:20952657) . Expressed in intraepithelial CD8-positive T cell subsets with higher frequency in gamma-delta T cells than alpha-beta T cells (at protein level) (PubMed:18064301) . Expressed in memory gamma-delta T cells (at protein level) (PubMed:20952657) . Restricted to a subset of memory/effector CD8-positive alpha-beta T cells (at protein level) (PubMed:12387742) Expressed in intratumoral NK and CD8-positive T cells (PubMed:30503213) . Expressed in melanoma-specific cytotoxic T cell clones (at protein level) (PubMed:9485206) . KLRD1-KLRC1 and KLRD1-KLRC2 are differentially expressed in NK and T cell populations, with only minor subsets expressing both receptor complexes (at protein level) (PubMed:20952657) .

Synonyms

NKG2-A/NKG2-B type II integral membrane protein, CD159 antigen-like family member A, NK cell receptor A, NKG2-A/B-activating NK receptor, CD159a, KLRC1, NKG2A

Gene Name

KLRC1

Gene ID

3821

UniProt

P26715

Chromosomal Location

Cell membrane; Single-pass type II membrane protein

Applications

WB, IF

Dilution

WB--1:1000 IF--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

94866501808357694302209485206121655209486650943022094852063086098412387742180643013050321330860984

Molecular Weight

26314

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KLRC1 Antibody (N-term) [APR03712G].

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=3821

Uniprot URL

https://www.uniprot.org/uniprot/P26715

Available Sizes

Curated Selection

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