TNFAIP8L3 Antibody (Center) [APR03623G]
Product Specifications
Background
Tissue Location: Widely expressed (at protein level) (PubMed:25479791) . Highly expressed in most carcinoma cell lines (PubMed:25479791, PubMed:25242044) .
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TNFAIP8L3 Antibody (Center) [APR03623G].
Synonyms
Tumor necrosis factor alpha-induced protein 8-like protein 3, TNF alpha-induced protein 8-like protein 3, TNFAIP8-like protein 3, TNFAIP8L3
Gene Name
TNFAIP8L3
Gene ID
388121
UniProt
Q5GJ75
Chromosomal Location
Cytoplasm. Cell membrane {ECO:0000250|UniProtKB:Q3TBL6}. Note=On PDGF activation, translocates from cytoplasm to plasma membrane {ECO:0000250|UniProtKB:Q3TBL6}
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling.
Molecular Weight
32659
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=388121
Uniprot URL
https://www.uniprot.org/uniprot/Q5GJ75
Available Sizes
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