LOC129293 Antibody (C-term) [APR03610G]
Product Specifications
Synonyms
Metalloprotease TIKI1, 34--, TRAB domain-containing protein 2A, TRABD2A, C2orf89, TIKI1
Gene Name
TRABD2A
Gene ID
129293
UniProt
Q86V40
Chromosomal Location
Cell membrane; Single-pass type I membrane protein
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.
Molecular Weight
57676
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LOC129293 Antibody (C-term) [APR03610G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=129293
Uniprot URL
https://www.uniprot.org/uniprot/Q86V40
Available Sizes
Curated Selection
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