GFER Antibody (C-term) [APR03596G]
Product Specifications
Background
Tissue Location: Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle
Synonyms
FAD-linked sulfhydryl oxidase ALR, Augmenter of liver regeneration, hERV1, Hepatopoietin, GFER, ALR, HERV1, HPO
Gene Name
GFER
Gene ID
2671
UniProt
P55789
Chromosomal Location
[Isoform 1]: Mitochondrion intermembrane space. Mitochondrion
Applications
WB, FC
Dilution
WB--1:1000 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
[Isoform 1]: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen.
Molecular Weight
23449
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GFER Antibody (C-term) [APR03596G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2671
Uniprot URL
https://www.uniprot.org/uniprot/P55789
Available Sizes
Curated Selection
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