DDX11 Antibody (C-term) [APR03573G]

Tissue Location: Expressed in melanoma cells. Not detected in epidermal melanocytes of normal skin (at protein level) (PubMed:23116066) . Highly expressed in spleen, B-cells, thymus, testis, ovary, small intestine and pancreas (PubMed:9013641) . Very low expression seen in brain (PubMed:9013641) . Expressed in dividing cells and/or cells undergoing high levels of recombination (PubMed:9013641) No expression detected in cells signaled to terminally differentiate (PubMed:9013641) . Expressed weakly in keratinocytes (PubMed:8798685)

Probable ATP-dependent RNA helicase DDX11, CHL1-related protein 1, hCHLR1, DEAD/H box protein 11, Keratinocyte growth factor-regulated gene 2 protein, KRG-2, DDX11, CHL1, CHLR1, KRG2

Nucleus. Nucleus, nucleolus. Cytoplasm, cytoskeleton, spindle pole. Midbody Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=During the early stages of mitosis, localizes to condensed chromatin and is released from the chromatin with progression to metaphase. Also localizes to the spindle poles throughout mitosis and at the midbody at later stages of mitosis (metaphase to telophase) (PubMed:17105772) . In interphase, colocalizes with nucleolin in the nucleolus (PubMed:26089203)

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

106487832185477023797032260892032650324518499658221024141849965822102414265032452379703226503245171057721849965820124417231160662379703218499658274779082185477026089203231160662747790890136411849965822102414

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DDX11 Antibody (C-term) [APR03573G].