ANAPC5 Antibody (Center) [APR03506G]
Product Specifications
Synonyms
Anaphase-promoting complex subunit 5, APC5, Cyclosome subunit 5, ANAPC5, APC5
Gene Name
ANAPC5
Gene ID
51433
UniProt
Q9UJX4
Chromosomal Location
Nucleus. Cytoplasm, cytoskeleton, spindle
Applications
WB, FC
Dilution
WB--1:1000 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Molecular Weight
85077
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ANAPC5 Antibody (Center) [APR03506G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=51433
Uniprot URL
https://www.uniprot.org/uniprot/Q9UJX4
Available Sizes
Curated Selection
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