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ANAPC5 Antibody (Center) [APR03506G]

Selected Variant

APR03506G-01

Size: 50 µL

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ANAPC5 Antibody (Center) [APR03506G].

Synonyms

Anaphase-promoting complex subunit 5, APC5, Cyclosome subunit 5, ANAPC5, APC5

Gene Name

ANAPC5

Gene ID

51433

UniProt

Q9UJX4

Chromosomal Location

Nucleus. Cytoplasm, cytoskeleton, spindle

Applications

WB, FC

Dilution

WB--1:1000 FC--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Molecular Weight

85077

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=51433

Uniprot URL

https://www.uniprot.org/uniprot/Q9UJX4

Available Sizes

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