GSDMC Antibody (Center) [APR03477G]
Product Specifications
Background
Tissue Location: Expressed mainly in trachea and spleen (PubMed:11223543) . In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium (PubMed:19051310) .
Synonyms
Gasdermin-C, Melanoma-derived leucine zipper-containing extranuclear factor, GSDMC, MLZE
Gene Name
GSDMC {ECO:0000303|PubMed:17350798, ECO:0000312|HGNC:HGNC:7151}
Gene ID
56169
UniProt
Q9BYG8
Chromosomal Location
[Gasdermin-C]: Cytoplasm, cytosol
Applications
WB, IHC-P, FC
Dilution
FC--1:25 WB--1:2000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
[Gasdermin-C]: This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-C, N-terminal) binds to membranes and forms pores, triggering cell death.
Molecular Weight
57692
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GSDMC Antibody (Center) [APR03477G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=56169
Uniprot URL
https://www.uniprot.org/uniprot/Q9BYG8
Available Sizes
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