ANGPT2 Antibody (C-term) [APR03419G]
Product Specifications
Synonyms
Angiopoietin-2, ANG-2, ANGPT2
Gene Name
ANGPT2
Gene ID
285
UniProt
O15123
Chromosomal Location
Secreted.
Applications
WB, FC
Dilution
WB--1:500 WB--1:1000 FC--1:25 IHC-P--1:100~500 WB--1:2000 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Molecular Weight
56919
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ANGPT2 Antibody (C-term) [APR03419G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=285
Uniprot URL
https://www.uniprot.org/uniprot/O15123
Available Sizes
Curated Selection
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