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Procyanidin B-5 3,3'-di-O-gallate

Selected Variant

HY-N9777-01

Size: 1 mg

Procyanidin B-5 3,3'-di-O-gallate is a potent inhibitor of squalene epoxidase with an IC50 of 0.55 μM. Procyanidin B-5 3,3'-di-O-gallate reduces cholesterol by inhibiting squalene epoxidase activity[1].

Product Specifications

CAS Number

106533-60-2

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/procyanidin-b-5-3-3-di-o-gallate.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC(O)=C(C(O)=C1)O)O[C@@H]2[C@@H](C3=C(O)C=C(O[C@H](C4=CC(O)=C(C=C4)O)[C@@H](C5)OC(C6=CC(O)=C(C(O)=C6)O)=O)C5=C3O)C7=C(O)C=C(O)C=C7O[C@@H]2C8=CC(O)=C(C=C8)O

Molecular Formula

C44H34O20

Molecular Weight

882.73

References & Citations

[1]Abe I, et al. Galloyl esters from rhubarb are potent inhibitors of squalene epoxidase, a key enzyme in cholesterol biosynthesis. Planta Med. 2000 Dec;66 (8) :753-6.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Price

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