Contulakin G
Contulakin G is an O-glycosylated invertebrate neurotensin. Contulakin-G is a weaker agonist for the neurotensin receptor. Contulakin G is also a potent antinociceptive agent[1][2].
Product Specifications
CAS Number
229180-41-0
UNSPSC
12352209
Target
Neurotensin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/contulakin-g.html
Solubility
H2O
Smiles
CC(N[C@@H]1[C@H]([C@H]([C@H](O[C@@H]1O[C@H](C)[C@H](NC([C@H](C)NC([C@H](CC(N)=O)NC([C@H](CO)NC(CNC(CNC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CO)NC([C@H]2NC(CC2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N3[C@@H](CCC3)C(N[C@H](C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC(C)C)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)=O)CO)O)O[C@@H]5O[C@@H]([C@@H]([C@@H]([C@H]5O)O)O)CO)=O
Molecular Formula
C88H140N20O37
Molecular Weight
2070.17
References & Citations
[1]Lee HK, et al. A marine analgesic peptide, Contulakin-G, and neurotensin are distinct agonists for neurotensin receptors: uncovering structural determinants of desensitization properties. Front Pharmacol. 2015 Feb 10;6:11.|[2]Allen JW, et al. An assessment of the antinociceptive efficacy of intrathecal and epidural contulakin-G in rats and dogs. Anesth Analg. 2007 Jun;104 (6) :1505-13, table of contents.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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