Sodium Channel inhibitor 5
Sodium Channel inhibitor 5 (compound 7d) is a potent inhibitor of sodium channel, with the IC50 of 2.7 μM. Sodium Channel inhibitor 5 plays an important role in antiarrhythmic research[1].
Product Specifications
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sodium-channel-inhibitor-5.html
Smiles
O=C1N(CCN(CCOC2=CC=C(C3=CC=CC(C(F)(F)F)=C3)C=C2)C1)CC4=NC=CC=N4
Molecular Formula
C24H23F3N4O2
Molecular Weight
456.46
References & Citations
[1]Hui Yang, et al. 1,4-Disubstituted Piperazin-2-Ones as Selective Late Sodium Current Inhibitors with QT Interval Shortening Properties in Isolated Rabbit Hearts. J Med Chem. 2024 May 17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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