Sodium Channel inhibitor 5

Sodium Channel inhibitor 5 (compound 7d) is a potent inhibitor of sodium channel, with the IC50 of 2.7 μM. Sodium Channel inhibitor 5 plays an important role in antiarrhythmic research[1].

Product Specifications

UNSPSC

12352005

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/sodium-channel-inhibitor-5.html

Smiles

O=C1N(CCN(CCOC2=CC=C(C3=CC=CC(C(F)(F)F)=C3)C=C2)C1)CC4=NC=CC=N4

Molecular Formula

C24H23F3N4O2

Molecular Weight

456.46

References & Citations

[1]Hui Yang, et al. 1,4-Disubstituted Piperazin-2-Ones as Selective Late Sodium Current Inhibitors with QT Interval Shortening Properties in Isolated Rabbit Hearts. J Med Chem. 2024 May 17.