Sodium Channel inhibitor 5
Sodium Channel inhibitor 5 (compound 7d) is a potent inhibitor of sodium channel, with the IC50 of 2.7 μM. Sodium Channel inhibitor 5 plays an important role in antiarrhythmic research[1].
Product Specifications
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sodium-channel-inhibitor-5.html
Smiles
O=C1N(CCN(CCOC2=CC=C(C3=CC=CC(C(F)(F)F)=C3)C=C2)C1)CC4=NC=CC=N4
Molecular Formula
C24H23F3N4O2
Molecular Weight
456.46
References & Citations
[1]Hui Yang, et al. 1,4-Disubstituted Piperazin-2-Ones as Selective Late Sodium Current Inhibitors with QT Interval Shortening Properties in Isolated Rabbit Hearts. J Med Chem. 2024 May 17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV780742 1.0 µg DNA
RPL36AP38 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)
Sign In for Pricing
View Details 
PH312810 10 µg
Protein Kinase A reguLatory subunit I alpha (PRKAR1A) (NM_212472) Human Mass Spec Standard
Sign In for Pricing
View Details E9050-44A-ML650 100 µL
EYA2 (Eyes Absent Homolog 2, EAB1) (MaxLight 650)
Sign In for Pricing
View Details MBS1245594-01 0.02 mg (E-Coli)
Recombinant Human 25-hydroxycholesterol 7-alpha-hydroxylase (CYP7B1)
Sign In for Pricing
View Details MBS1245594-02 0.02 mg (Yeast)
Recombinant Human 25-hydroxycholesterol 7-alpha-hydroxylase (CYP7B1)
Sign In for Pricing
View Details