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N-Boc-5-bromoindole

N-Boc-5-bromoindole is formed as an intermediate for the synthesis of di-Boc-protected 5-aminoindole via a Buchwald-Hartwig amination with tBu-carbamate followed by regioselective bromination[1].

Product Specifications

CAS Number

[182344-70-3]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/n-boc-5-bromoindole.html

Purity

99.98

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(OC(C)(C)C)N1C=CC2=C1C=CC(Br)=C2

Molecular Formula

C13H14BrNO2

Molecular Weight

296.16

Precautions

H315, H319, H335

References & Citations

[1]Christoffer Bengtsson, et al. Rapid Construction of a Chloromethyl-Substituted Duocarmycin-like Prodrug. Molecules. 2023 Jun 16;28 (12) :4818.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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